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Helmholtz Zentrum München

Helmholtz Zentrum München is the German Research Center for Environmental Health. It investigates important common diseases which develop from the interaction of lifestyle, environmental factors and personal genetic background, focusing particularly on diabetes mellitus, allergies and chronic lung diseases.

Helmholtz Zentrum München is a research institution of the Federal Republic of Germany and the Free State of Bavaria. It is a member of the Helmholtz Association of German Research Centers.

Ali Ertürk
Director of the Institute of Tissue Engineering and Regenerative Medicine
Helmholtz Zentrum München
March 11, 2025
SCP-Nano: A new technology to visualize nanocarriers in cells and tissues
NOMIS researcher Ali Ertürk and fellow scientists at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have developed a technology that enables the precise detection of nanocarriers — tiny […]
July 13, 2024
Mapping the body: Deep 3D histology powered by tissue clearing, omics and AI
In a Nature Methods perspective, NOMIS researcher Ali Ertürk addresses the new era of 3D-omics by tissue clearing and AI, called deep 3D histology. He writes that “biomedical research needs […]
July 11, 2023
Whole-body cellular mapping in mouse using standard IgG antibodies
NOMIS researcher Ali Ertürk and colleagues have developed a new chemical method, wildDISCO, that uses conventional antibodies and fluorescent markers to image a mouse’s entire body. This revolutionary technique provides […]
January 9, 2023
Novel spatial-omics technology enables investigation of diseases at their early stages
NOMIS researcher Ali Ertürk, Matthias Mann and their colleagues have developed a new technology that combines methods to turn mouse and human tissues transparent with the latest robotics and proteomics […]
January 14, 2025
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning
Abstract: Efficient and accurate nanocarrier development for targeted drug delivery is hindered by a lack of methods to analyze its cell-level biodistribution across whole organisms. Here we present Single Cell Precision […]
December 11, 2024
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Abstract: SARS-CoV-2 infection is associated with long-lasting neurological symptoms, although the underlying mechanisms remain unclear. Using optical clearing and imaging, we observed the accumulation of SARS-CoV-2 spike protein in the skull-meninges-brain […]
July 12, 2024
Deep 3D histology powered by tissue clearing, omics and AI
Abstract: To comprehensively understand tissue and organism physiology and pathophysiology, it is essential to create complete three-dimensional (3D) cellular maps. These maps require structural data, such as the 3D configuration and […]
December 22, 2022
Spatial proteomics in three-dimensional intact specimens
Abstract: Spatial molecular profiling of complex tissues is essential to investigate cellular function in physiological and pathological states. However, methods for molecular analysis of large biological specimens imaged in 3D are […]
SCP-Nano: A new technology to visualize nanocarriers in cells and tissues
News
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning
Insight
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Insight
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