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Victoria Orphan

Victoria Orphan

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Victoria Orphan is a 2018 NOMIS awardee. She is the James Irvine Professor of Environmental Science and Geobiology in the Division of Geological and Planetary Sciences at the California Institute of Technology (Caltech; Pasadena, US).

Born in the US, Orphan earned a BA in aquatic biology in 1994 and a PhD in ecology, evolution and marine biology in 2001 from the University of California, Santa Barbara. She did postdoctoral research as a National Research Council Associate at the NASA Ames Research Center in California from 2002 to 2004. She has been on the faculty at Caltech since 2004. Her work on microbially mediated anaerobic oxidation of methane in deep-sea sediment has won her the prestigious MacArthur Fellowship (known as the “genius grant”). She is also the recipient of the 2010 Presidential Early Career Award for Scientists and Engineers and the Gordon and Betty Moore Foundation Investigator Award, among many others.

Orphan is a pioneer of techniques that combine molecular biology and mass spectrometry into novel methods that enable the capture and analysis of individual microbial cells in their natural environments. She is studying the interaction of microorganisms found in deep-sea sediment with the environment, and has shown that some of these microbes work together in symbiosis to regulate greenhouse gases in the atmosphere by consuming methane as their primary source of carbon. Her project, Understanding Virus-Host Dynamics in Ocean Ecosystems, is investigating the impact of marine viruses on the transformation of carbon, nitrogen and sulfur in ocean surface waters and sediments, with the ultimate goal of incorporating the data from this unique stable isotope approach into trophic models for ocean ecosystems. This work is advancing the viral-nanoSIMS method for multi-isotope and stable isotope labeling and tracking of host-virus dynamics at the nanometer scale.

Victoria Orphan | Awards Film

Victoria Orphan | Insights Film

Victoria Orphan's News

The NOMIS Distinguished Scientist and Scholar Award is the topic of a recently published advertorial in Science. The 2023 NOMIS Awardees, Anne Brunet and David Autor, explain how the NOMIS […]

As part of Conversations on Sustainability, a webinar series hosted by the Caltech Science Exchange, Dianne Newman, Gordon M. Binder/Amgen Professor of Biology and Geobiology and Ecology and Biosphere Engineering Initiative Lead for […]

Victoria Orphan's Insights

Abstract: ‘Candidatus Methanophagales’ (ANME-1) is an order-level clade of archaea responsible for anaerobic methane oxidation in deep-sea sediments. The diversity, ecology and evolution of ANME-1 remain poorly understood. In this study, we use metagenomics on deep-sea hydrothermal samples to expand ANME-1 diversity and uncover the effect of virus–host dynamics. Phylogenetic analyses