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University Children's Hospital Zurich

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The University Children’s Hospital Zurich is a nonprofit private institution serving all children and adolescents. It is the largest children’s hospital in Switzerland and one of Europe’s leading centers for pediatric and adolescent medicine.

Luregn Schlapbach
Head of the Pediatric and Neonatal Intensive Care Unit
University Children's Hospital Zurich
August 26, 2024
Luregn Schlapbach leads The Lancet series on pediatric sepsis
NOMIS researcher Luregn Schlapbach was invited by The Lancet to lead a series on pediatric sepsis, a life-threatening response to infection. The four articles in this series put forth the […]
January 27, 2024
New global criteria for improved diagnosis of pediatric sepsis
Diagnosis of sepsis in children has been improved based on new research findings by NOMIS researcher Luregn Schlapbach and colleagues. An international research team co-led by the University Children’s Hospital […]
June 26, 2023
Machine learning to predict poor school performance in paediatric survivors of intensive care
NOMIS researcher Luregn Schlapbach and colleagues have developed a machine learning model to predict poor school outcomes in children surviving the intensive care unit (ICU). Their findings were published in […]
February 10, 2023
Researchers show methylprednisolone could be effective, readily available treatment for PIMS
In a study on children with PIMS-TS, an inflammatory disease that occurs in children following infection with SARS-CoV-2, NOMIS researcher Luregn Schlapbach and colleagues have found that the steroid methylprednisolone […]
February 6, 2023
Pragmatic trials for critical illness in neonates and children
In a comment published in The Lancet Child & Adolescent Health, NOMIS researcher Luregn Schlapbach and colleague Mark J. Peters address the serious issues related to a lack of high-grade […]
September 16, 2022
Switzerland releases Sepsis National Action Plan
Led by NOMIS researcher Luregn Schlapbach, a group of over 40 national experts assembled a Swiss Sepsis National Action Plan. Enhancing innovative research that drives cutting-edge ideas from the bench […]
June 10, 2022
Time to tackle early-onset sepsis in low-income and middle-income countries
NOMIS researcher Luregn Schlapbach and colleagues have published a commentary on the results from the Burden of Antibiotics Resistance in Neonates from Developing Societies (BARNARDS) study, which were presented in […]
January 10, 2022
Neonatal sepsis: WHO-recommended Rx needs a major rethink
NOMIS researcher Luregn Schlapbach and colleagues have published a commentary in The Lancet Infectious Diseases, responding to recent findings that suggest the current treatment for neonatal sepsis in low- and […]
May 28, 2021
Generating new insights to enable evidenced-based interventions for children with PIMS-TS
NOMIS researcher Luregn Schlapbach and colleagues have published best practice guidelines based on currently available knowledge to standardize treatment of children with suspected PIMS-TS. Background: Following the spread of the coronavirus […]
September 1, 2024
Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world
Abstract: The digitisation of health care is offering the promise of transforming the management of paediatric sepsis, which is a major source of morbidity and mortality in children worldwide. Digital technology […]
September 1, 2024
Quality improvement programmes in paediatric sepsis from a global perspective
Abstract: Sepsis is a major contributor to poor child health outcomes around the world. The high morbidity, mortality, and societal cost associated with paediatric sepsis render it a global health priority, […]
September 1, 2024
Susceptibility to childhood sepsis, contemporary management, and future directions
Abstract: Sepsis disproportionally affects children across all health-care settings and is one of the leading causes of morbidity and mortality in neonatal and paediatric age groups. As shown in the first […]
September 1, 2024
The burden and contemporary epidemiology of sepsis in children
Abstract: Sepsis is a dysregulated host response to infection that leads to life-threatening organ dysfunction. Half of the 50 million people affected by sepsis globally every year are neonates and children […]
January 21, 2024
International Consensus Criteria for Pediatric Sepsis and Septic Shock
Abstract: Importance Sepsis is a leading cause of death among children worldwide. Current pediatric-specific criteria for sepsis were published in 2005 based on expert opinion. In 2016, the Third International Consensus Definitions […]
January 21, 2024
Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock
Abstract: Importance The Society of Critical Care Medicine Pediatric Sepsis Definition Task Force sought to develop and validate new clinical criteria for pediatric sepsis and septic shock using measures of organ dysfunction […]
May 20, 2022
Multicenter Randomized Trial of Methylprednisolone vs. Intravenous Immunoglobulins to Treat the Pediatric Inflammatory Multisystem Syndrome—Temporally Associated With SARS-CoV-2 (PIMS-TS): Protocol of the Swissped RECOVERY Trial
Abstract: Introduction: In 2020, a new disease entitled Pediatric Inflammatory Multisystem Syndrome temporally associated with COVID-19 (PIMS-TS), or Multisystem Inflammatory Syndrome in Children (MIS-C), emerged, with thousands of children affected globally. […]
May 26, 2021
Best Practice Recommendations for the Diagnosis and Management of Children With Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 (PIMS-TS; Multisystem Inflammatory Syndrome in Children, MIS-C) in Switzerland
Abstract: Background: Following the spread of the coronavirus disease 2019 (COVID-19) pandemic a new disease entity emerged, defined as Pediatric Inflammatory Multisystem Syndrome temporally associated with COVID-19 (PIMS-TS), or Multisystem Inflammatory […]
Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world
Insight
Quality improvement programmes in paediatric sepsis from a global perspective
Insight
Susceptibility to childhood sepsis, contemporary management, and future directions
Insight
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