Susan Kaech

Susan Kaech's Profile

Name Susan Kaech
About Me Susan Kaech aims to understand how memory T cells are produced during infection and vaccination, how they function and why they can fail to induce long-term immunity during immunization. Her lab has been a leader in using genetic and molecular tools to identify the genes and signaling molecules involved in generating two specific types of memory T cells, CD4 and CD8, from precursor cells during both acute and chronic viral infections. She and her team discovered more than half a dozen important regulatory genes, as well as several types of key molecules called cytokines, which influence memory T cell development. Kaech is also interested in how T cells are metabolically regulated, and how their differentiation and function can be altered by nutrient availability during infection and in tumors. In particular, she seeks to learn how T cell behavior is suppressed by tumors, in order to create better therapies for cancer using the body's own immune system—an innovative and rapidly moving field called cancer immunotherapy. EDUCATION PhD, Developmental Biology, Stanford University BS, Cellular and Molecular Biology, University of Washington, Seattle, WA AWARDS & HONORS 2009 Howard Hughes Early Career Scientist 2007 Presidential Early Career Award for Scientists and Engineers (PECASE) 2007 American Asthma Foundation Investigator 2005 Cancer Research Institute Investigator Award 2005 Edward Mallinckrodt Jr. Foundation Award 2003 Burroughs-Wellcome Foundation Award in Biomedical Sciences 1999 Damon Runyon-Walter Winchell Cancer Research Fellowship 1993 National Science Foundation Predoctoral Fellowship